Senior Principal Scientist Salary in San Francisco, California

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How much does a Senior Principal Scientist make in San Francisco, CA? The average Senior Principal Scientist salary in San Francisco, CA is $225,258 as of April 01, 2025, but the salary range typically falls between $202,350 and $245,793. Salary ranges can vary widely depending on many important factors, including education, certifications, additional skills, the number of years you have spent in your profession. With more online, real-time compensation data than any other website, Salary.com helps you determine your exact pay target. 

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25% $202,350 10% $181,494 90% $264,488 75% $245,793 $225,258 50%(Median)
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Senior Principal Scientist

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Job Openings for Senior Principal Scientist in San Francisco, CA
MSAT Scientist III/ Senior Scientist
Lonza - BROOKSIDE VILLAGE , TX
Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there’s no magic formula to how we do it. Our great
- 35 days ago
Senior Research Scientist - Material Flammability, Fire Dynamics and Lithium-ion Battery Safety
FM - NORWOOD , MA
FM is a leading property insurer of the world's largest businesses, providing more than one-third of FORTUNE 1000-size companies with engineering-based risk man
- 4 days ago
Senior Research Scientist Explosion Protection
FM - NORWOOD , MA
FM is a leading property insurer of the world's largest businesses, providing more than one-third of FORTUNE 1000-size companies with engineering-based risk man
- 4 days ago
Sr Operations Research Scientist - Supply Chain Network Optimization (Simulation, Optimization, Data Pipelining)
Target - MINNEAPOLIS , MN
The pay range is $95,000.00 - $171,000.00. Pay is based on several factors which vary based on position. These include labor markets and in some instances may i
- 5 days ago
Principal / Sr. Principal Data Scientist (AHT) with Security Clearance
Northrop Grumman - BELLEVUE , NE
RELOCATION ASSISTANCE: Relocation assistance may be available CLEARANCE TYPE: Secret TRAVEL: No Description At Northrop Grumman, our employees have incredible o
- 1 day ago
Principal Data Scientist/ Sr. Principal Data Scientist with Security Clearance
Northrop Grumman - PALMDALE , CA
RELOCATION ASSISTANCE: Relocation assistance may be available CLEARANCE TYPE: Secret TRAVEL: Yes, 10% of the Time Description At Northrop Grumman, our employees
- 1 day ago

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Understand the total compensation opportunity for a Senior Principal Scientist, base salary plus other pay elements

Average Base Salary

Core compensation

 
 
 
202350
245793
225258

Average Total Cash Compensation

Includes base and annual incentives

 
 
 
225694
282262
250577
These charts show the average base salary (core compensation), as well as the average total cash compensation for the job of Senior Principal Scientist in San Francisco, CA. The base salary for Senior Principal Scientist ranges from $202,350 to $245,793 with the average base salary of $225,258. The total cash compensation, which includes base, and annual incentives, can vary anywhere from $225,694 to $282,262 with the average total cash compensation of $250,577.

Discover how your pay is adjusted for skills, experience, and other factors

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For a real-time salary target, tell us more about your role in the four categories below.

202350
245793

 

About San Francisco, California    San Francisco is located on the West Coast of the United States at the north end of the San Francisco Peninsula and includes significant stretches of ....More

San Francisco, California  area prices were up 4.5% from a year ago

Senior Principal Scientist Salary in popular cities: Los Angeles, San Diego, San Jose

Skills associated with Senior Principal Scientist: Across

Recently searched related titles: Data Science Team Lead

Learn more about: Compensation Packages, Employee Flight Risk, Gender Pay Gap, Job Openings for This Role

Jobs with a similar salary range to Senior Principal Scientist : Senior Principal Data Scientist, Computational Science