Principal Scientist, Medicinal Chemistry Salary in the United States

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How much does a Principal Scientist, Medicinal Chemistry make in the United States? The average Principal Scientist, Medicinal Chemistry salary in the United States is $154,369 as of April 01, 2025, but the salary range typically falls between $139,350 and $170,680. Salary ranges can vary widely depending on many important factors, including education, certifications, additional skills, the number of years you have spent in your profession. With more online, real-time compensation data than any other website, Salary.com helps you determine your exact pay target. 

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25% $139,350 10% $125,676 90% $185,531 75% $170,680 $154,369 50%(Median)
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Principal Scientist, Medicinal Chemistry

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See user submitted job responsibilities for Principal Scientist, Medicinal Chemistry.

Search Principal Scientist, Medicinal Chemistry Job Openings

Job Openings for Principal Scientist, Medicinal Chemistry
Product Safety Scientist
Sally Beauty Holdings - DENTON , TX
Overview. Essential Function. This position provides technical expertise for product safety assessments and ensures chemical ingredient regulatory compliance. T
- 92 days ago
Research Scientist (Chemistry) - AI Trainer
DataAnnotation - SAINT PAUL , MN
We are looking for an *advanced chemist* to join our team to train AI models. You will measure the progress of these AI chatbots, evaluate their logic, and solv
- 81 days ago
Teacher of Chemistry - AI Trainer
DataAnnotation - ESCONDIDO , CA
We are looking for a chemistry educator to join our team to train AI models. You will measure the progress of these AI chatbots, evaluate their logic, and solve
- 135 days ago
Graduate Research Intern Chemistry - AI Trainer
DataAnnotation - TULSA , OK
We are looking for an *advanced chemist* to join our team to train AI models. You will measure the progress of these AI chatbots, evaluate their logic, and solv
- 81 days ago
Clinical Laboratory Scientist II, Lab AdminGeneral - PRN
CHRISTUS Health - LAKE CHARLES , LA
Description Summary: This Job performs all routine and complicated laboratory procedures including specimen processing and handling, testing of patient specimen
- 8 days ago
Clinical Laboratory Scientist II-Lab AdminGeneral-PRN
Christus Health - EDGEFIELD , LA
Description Summary: This Job performs all routine and complicated laboratory procedures including specimen processing and handling, testing of patient specimen
- 21 days ago

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Understand the total compensation opportunity for a Principal Scientist, Medicinal Chemistry, base salary plus other pay elements

Average Base Salary

Core compensation

 
 
 
139350
170680
154369

Average Total Cash Compensation

Includes base and annual incentives

 
 
 
147338
176688
161721
These charts show the average base salary (core compensation), as well as the average total cash compensation for the job of Principal Scientist, Medicinal Chemistry in the United States. The base salary for Principal Scientist, Medicinal Chemistry ranges from $139,350 to $170,680 with the average base salary of $154,369. The total cash compensation, which includes base, and annual incentives, can vary anywhere from $147,338 to $176,688 with the average total cash compensation of $161,721.

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For a real-time salary target, tell us more about your role in the four categories below.

139350
170680

 

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